3:15 PM - 4:00 PM
Genetics and Addiction Science

 Kenneth Blum, PhD

Michael V. Genovese, MD, JD

Session Description:

The single nucleotide polymorphisms (SNPs) also known as sequence variations and how they effects genetic and epigenetic function in Addiction will be described. Illustrations of the Brain Reward Cascade and Reward Deficiency Syndrome (RDS) will be used to explain the mechanism of reward deficiency as the basis of selection of genes for the Genetic Addiction Risk Score (GARS) panel. The results of research that lead to the selection of the sequence variations of the genes used for the GARS test will be outlined. The clinical application and benefits of the GARS testing will be listed.

Learning Objectives:
  • Identify important neurotransmitters involved in the Brain Reward Cascade

  • Describe the RDS hypothesis/concept

  • Describe the research that led to the identification of the genetic basis of the GARS

  • Describe the GARS test